26 sept 2019

Polio outbreak in The Philippines caused by oral polio vaccine

Two cases have been reported both caused by vaccine derived type 2 (VDPV2). Environmental samples taken from sewage in Manila on 13 August and a waterway in Davao on 22 August.

The first polio case was confirmed on 14 September following testing by the National Polio Laboratory at the Research Institute for Tropical Medicine, the Japan National Institute of Infectious Diseases (NIID) and the United States Centers for Disease Control and Prevention (CDC).

The case-patient is a 3-year-old girl from Lanao del Sur in the southern Philippines. The virus isolated is genetically linked to VDPV2 previously isolated from environmental samples in Manila and Davao. This indicates that the virus is circulating.

The second polio case was confirmed on 19 September and is a 5-year-old boy from Laguna Province, approximately 100 km south-east of Metro Manila. Investigations and further characterization of the virus are ongoing.

Vaccine-derived polioviruses are forms of the poliovirus that have genetically changed from the attenuated (weakened) virus contained in oral polio vaccine.